For mutually beneficial cooperation the National Academic Bolshoi Opera and Ballet Theatre of the Republic of Belarus has signed a number of memorandums of cooperation with the largest opera houses of CIS and far abroad countries for effective development and strengthening of creative ties between the theatres in the field of ballet, opera and symphony art.

These memorandums provide for: organization of guest performances of both Parties; exchange of soloists and companies; joint projects on creation of ballet and opera productions; organization of masterclasses of leading artists of both theatres; participation in musical competitions and festivals; exchange of directors, conductors, designers, lighting designers, etc.; continual exchange of information on significant events in musical and theatrical life of both countries.

Since 2010, memorandums of bilateral cooperation with the following theaters have been signed:

- Alexander Spendiaryan Opera and Ballet National Theatre (Armenia);
- Alisher Navoi State Academic Bolshoi Theatre;
- Azerbaijan State Academic Opera and Ballet Theatre;
- Bolshoi Theatre of Russia;
- Deutsche Oper am Rhein Düsseldorf Duisburg;
- Estonian National Opera;
- Georgian National Opera and Ballet Theater of Tbilisi;
- Hungarian State Opera;
- Kolobov Novaya Opera Theatre of Moscow;
- Kyiv National Academic Theatre of Operetta;
- Latvian National Opera;
- Le Théâtre Lyrichorégra 20;
- Lithuanian National Opera and Ballet Theatre;
- Lodz Grand Theatre;
- Musical Theatre of the Republic of Karelia;
- National Centre for the Performing Arts (Beijing);
- National Theatre in Belgrade;
- National Theatre Brno;
- Novosibirsk State Academic Opera and Ballet Theatre;
- Odessa National Academic Theater of Opera and Ballet;
- Prague State Opera;
- Rudolf Nureyev Foundation;
- Samara Academic Opera and Ballet Theatre;
- Slovak National Theatre;
- Solomiya Krushelnytska Lviv State Academic Theatre of Opera and Ballet (Ukraine);
- Sofia National Opera and Ballet;
- Stanislavsky and Nemirovich-Danchenko Moscow Music Theatre;
- State Opera and Ballet Theatre “Astana Opera”;
- St. Petersburg State Academic Leonid Yacobson Ballet Theatre;
- Taras Shevchenko National Opera of Ukraine;
- Teatr Wielki Opera Narodowa.

Since 1994, the Bolshoi Theatre of Belarus has been working with conductor and producer Wilhelm Keitel and BNK Music Production GmbH.