Ekaterina Mikhnovets graduated in choral conducting from Grodno State Music College and in academic singing from the Belarusian State Academy of Music (2010) where she had studied under Valentina Rogovich.
In the 2015/2016 season, she was an apprentice of the opera company of the Bolshoi Theatre of Belarus.
She joined the opera company of the Bolshoi Theatre of Belarus in 2016.
Ekaterina Mikhnovets collaborates with a number of chamber and symphony orchestras, including the State Academic Symphony Orchestra of the Republic of Belarus, Chamber Soloists of Minsk conducted by Dmitry Zubkov, etc.

• The Partisan / Pathétique Memory Book to the music by Belarusian composers
• The Middle Sister, Weaver, Actress / The Tale of Tsar Saltan
• Marta, Laura / Iolanta
• Berta / Il barbiere di Siviglia
• The Snow Queen / The Story of Kai and Gerda (The Snow Queen) by Sergei Banevich
• Polina, the Governess / The Queen of Spades
• Maddalena, Giovanna / Rigoletto
• Lyubasha, Dunyasha, Petrovna / The Tsar’s Bride
• Marthe / Faust
• Orlofsky / Die Fledermaus
• Herodias / Salome
• Olga, the Nanny / Eugene Onegin
• Cherubino, Marcellina / The Marriage of Figaro
• The Third Lady / Die Zauberflöte
• Flora / La traviata
• Mezzo and alto parts in Johann Sebastian Bach’s Mass in B minor, The Magnificat and The St Matthew Passion, Giovanni Battista Pergolesi’s Stabat Mater, Requiem by Wolfgang Amadeus Mozart, The Symphony No. 3 in D minor by Gustav Mahler, Sergey Prokofiev’s cantata Alexander Nevsky, etc.

She took part in the Birgitta Festival in Tallinn, Estonia, in 2016 and in the Brucknerfest in Linz, Austria, in 2017. Later in 2017, Ekaterina participated in the Les Jeunes Ambassadeurs Lyriques programme in Montreal, Canada.
In 2018, she performed the role of the Nanny in the premiere of Eugene Onegin (conducted by Viktor Ploskina, directed by Oksana Taranenko) in Haifa, Israel.

In April 2025, she performed in Pathetic Diary of Memory as part of the Bolshoi Theatre of Belarus tour to the Bolshoi Theatre of Russia. The performance, which coincided with the Day of Unity of the Peoples of Belarus and Russia, was organised by the Ministry of Culture of the Russian Federation, the Ministry of Culture of the Republic of Belarus and the Standing Committee of the Union State with the participation of ROSCONCERT.